The Proceedings of the 46th Annual Conference on Computer Applications and Quantitative Methods in Archaeology, held between March 19th and 23th, 2018 at the University of Tübingen, Germany, discuss the current questions concerning digital recording, computer analysis, graphic and 3D visualization, data management and communication in the field of archaeology. Through a selection of diverse case studies from all over the world, the proceedings give an overview on new technical approaches and best practice from various archaeological and computer-science disciplines.