(E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells

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(E)-7-Ethylidene-lithocholic Acid (7-ELCA) Is a Potent Dual Farnesoid X Receptor (FXR) Antagonist and GPBAR1 Agonist Inhibiting FXR-Induced Gene Expression in Hepatocytes and Stimulating Glucagon-like Peptide-1 Secretion From Enteroendocrine Cells

Author: Stefela, Alzbeta; Kaspar, Miroslav; Drastik, Martin; Kronenberger, Thales; Micuda, Stanislav; Dracinsky, Martin; Klepetarova, Blanka; Kudova, Eva; Pavek, Petr
Tübinger Autor(en):
Kronenberger, Thales
Published in: Frontiers in Pharmacology (2021), Bd. 12, Article 713149
Verlagsangabe: Frontiers Media Sa
Language: English
Full text: http://dx.doi.org/10.3389/fphar.2021.713149
ISSN: 1663-9812
DDC Classifikation: 610 - Medicine and health
Dokumentart: Article
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