Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties

Stopper, Daniel; Biermann, Lukas; Watson, Paris R.; Li, Jingyu; Koenig, Beate; Gaynes, Matthew N.; Pessanha de Carvalho, Lais; Klose, Jana; Hanl, Maria; Hamacher, Alexandra; Schaeker-Huebner, Linda; Ramsbeck, Daniel; Held, Jana; Christianson, David W.; Kassack, Matthias U.; Hansen, Finn K.

dc.contributor.author	Pessanha de Carvalho, Lais
dc.contributor.author	Held, Jana
dc.date.accessioned	2025-12-16T10:31:56Z
dc.date.available	2025-12-16T10:31:56Z
dc.date.issued	2025
dc.identifier.issn	0022-2623
dc.identifier.uri	http://hdl.handle.net/10900/173162
dc.language.iso	en	de_DE
dc.publisher	Washington : Amer Chemical Soc	de_DE
dc.relation.uri	http://dx.doi.org/10.1021/acs.jmedchem.4c02373	de_DE
dc.subject.ddc	540	de_DE
dc.title	Exploring Alternative Zinc-Binding Groups in Histone Deacetylase (HDAC) Inhibitors Uncovers DS-103 as a Potent Ethylhydrazide-Based HDAC Inhibitor with Chemosensitizing Properties	de_DE
dc.type	Article	de_DE
utue.quellen.id	20250630000000_01720
utue.publikation.seiten	4426-4452	de_DE
utue.personen.roh	Stopper, Daniel
utue.personen.roh	Biermann, Lukas
utue.personen.roh	Watson, Paris R.
utue.personen.roh	Li, Jingyu
utue.personen.roh	Koenig, Beate
utue.personen.roh	Gaynes, Matthew N.
utue.personen.roh	Pessanha de Carvalho, Lais
utue.personen.roh	Klose, Jana
utue.personen.roh	Hanl, Maria
utue.personen.roh	Hamacher, Alexandra
utue.personen.roh	Schaeker-Huebner, Linda
utue.personen.roh	Ramsbeck, Daniel
utue.personen.roh	Held, Jana
utue.personen.roh	Christianson, David W.
utue.personen.roh	Kassack, Matthias U.
utue.personen.roh	Hansen, Finn K.
dcterms.isPartOf.ZSTitelID	Journal of Medicinal Chemistry	de_DE
dcterms.isPartOf.ZS-Issue	4	de_DE
dcterms.isPartOf.ZS-Volume	68	de_DE
utue.fakultaet	04 Medizinische Fakultät	de_DE